Scientific internships, awards, membership in scientific societies:

Fellowships:

• 2022 – fellowship in Leibniz Research Laboratories for Biotechnology and Artificial Organs (LEBAO), Hannover Medical School, Hannover, Germany (MINIATURA 5 grant fellowship)

Awards:

• Laureate of the 3rd degree team award of the Rector of the Jagiellonian University for academic teachers (2022)
• Laureate of the Individual Award of the Dean of FBB&B, Jagiellonian University for the scientific achievements in 2021 (2022)
• Laureate of the Krakow Branch Award of the Polish Society of Cell Biology for young scientists for an outstanding publication in the field of cell biology (2022)
• Laureate of the Individual Award of the Rector of the Jagiellonian University for commitment to work (2019)
• Circulation Research Award for the paper “Induced Pluripotent Stem Cell (iPSC)-Derived Extracellular Vesicles Are Safer and More Effective for Cardiac Repair Than iPSCs” (co-author; 2018)
• Three-time Laureate of the Jagiellonian University Rector's Scholarship for the best PhD students (2016-2018)
• Award for the best poster entitled “Transcriptomic and proteomic profiling identifies extracellular vesicles from iPS cells as potential therapeutic tool for cardiovascular disease”, World Conference on Regenerative Medicine, Leipzig, Germany (co-author; 2015)
• Award for the best poster entitled „Flow cytometry identification of novel sub-populations of cord blood-derived very small embryonic-like stem cells”, II Congress of the Polish Society of Cytometry, Kazimierz Dolny, Poland (main author; 2012)
• Award for the best oral presentation entitled "Antigenic analysis of cord blood-derived very small embryonic-like stem cells", Collegium Medicum PhD Conference, Krakow (main author; 2012)

Scientific interest:

• Stem cells
• Extracellular vesicles
• Flow cytometry
• Hematopoiesis
• Regenerative medicine

Didactics:

• Essential Aspects of Cell Biology (WBT-MBT2-1E)
• Introduction to Stem Cell Biology (WBT-400E)
• Komórki macierzyste - zastosowania w biotechnologii i medycynie (WBT-208)
• Practicum in cell biology (WBT-398E)
• Praktikum z cytochemii (BCH-395)
• oraz pracownie licencjackie i magisterskie w Zakładzie Biologii Komórki

Selected publications:

1. Kolcz J* , Karnas E* , Madeja  Z, Zuba-Surma EK. (2022) The cardioprotective and anti-inflammatory effect of inhaled nitric oxide during Fontan surgery in patients with single ventricle congenital heart defects: a prospective randomized study. J Intensive Care, 2022 Oct 13;10(1):48. https://doi.org/10.1186/s40560-022-00639-y *equally contributed
2. Karnas E, Sekuła-Stryjewska M, Kmiotek-Wasylewska K, Bobis-Wozowicz S, Ryszawy D, Sarna M, Madeja Z, Zuba-Surma EK. (2021). Extracellular vesicles from human iPSCs enhance reconstitution capacity of cord blood-derived hematopoietic stem and progenitor cells. Leukemia, 35(10):2964-2977. https://doi.org/10.1038/s41375-021-01325-y
3. Bryk M, Karnas E, Mlost J, Zuba-Surma E, Starowicz K. (2021). Mesenchymal stem cells and extracellular vesicles for the treatment of pain: Current status and perspectives. Br J Pharmacol, https://doi.org/10.1111/bph.15569
4. Karkowska-Kuleta J, Kulig K, Karnas E, Zuba-Surma E, Woznicka O, Pyza E, Kuleta P, Osyczka A, Rapala-Kozik M, Kozik A. (2020). Characteristics of Extracellular Vesicles Released by the Pathogenic Yeast-Like Fungi Candida glabrata, Candida parapsilosis and Candida tropicalis. Cells, 9(7):1722. https://doi.org/10.3390/cells9071722
5. Wróbel T, Luty M, Catapano J, Karnas E, Szczygieł M, Piwowarczyk K, Ryszawy D, Drabik G, Zuba-Surma E, Siedlar M, Madeja Z, Elas M, Czyż J. (2020). CD44+ cells determine fenofibrate-induced microevolution of drug-resistance in prostate cancer cell populations. Stem Cells, 38(12):1544–56. https://doi.org/10.1002/stem.3281
6. Czamara K, Karnas E, Majka Z, Wojcik T, Zuba-Surma EK, Baranska M, Kaczor A. (2019). Impact of cell cycle dynamics on pathology recognition: Raman imaging study. J Biophotonics, 12(2):e201800152. https://doi.org/10.1002/jbio.201800152
7. Adamiak M, Cheng G, Bobis-Wozowicz S, Zhao L, Kedracka-Krok S, Samanta A, Karnas E, Xuan YT, Skupien-Rabian B, Chen X, Jankowska U, Girgis M, Sekula M, Davani A, Lasota S, Vincent RJ, Sarna M, Newell KL, Wang OL, Dudley N, Madeja Z, Dawn B, Zuba-Surma EK. (2018). Induced Pluripotent Stem Cell (iPSC)-Derived Extracellular Vesicles Are Safer and More Effective for Cardiac Repair Than iPSCs. Circ Res, 122(2):296-309. https://doi.org/10.1161/CIRCRESAHA.117.311769
8. Bobis-Wozowicz S, Kmiotek K, Kania K, Karnas E, Labedz-Maslowska A, Sekula M, Kedracka-Krok S, Kolcz J, Boruczkowski D, Madeja Z, Zuba-Surma EK. (2017). Diverse impact of xeno-free conditions on biological and regenerative properties of hUC-MSCs and their extracellular vesicles. J Mol Med (Berl), 95(2):205-220. https://doi.org/10.1007/s00109-016-1471-7
9. Labedz-Maslowska A, Kamycka E, Bobis-Wozowicz S, Madeja Z, Zuba-Surma EK. (2016). Identification of New Rat Bone Marrow-Derived Population of Very Small Stem Cell with Oct-4A and Nanog Expression by Flow Cytometric Platforms. Stem Cells Int, 2016:5069857. doi: 10.1155/2016/5069857. https://doi.org/10.1155/2016/5069857
10. Faryan M, Kamycka E, Mizia-Stec K, Wojakowski W, Wybraniec M, Hoffmann A, Nowak S, Kolasa J, Zuba-Surma E, Wnuk-Wojnar AM. (2016). Mobilization of stem and progenitor cells in patients with atrial fibrillation undergoing circumferential pulmonary vein isolation. Int J Cardiol, 203:415-7. https://doi.org/10.1016/j.ijcard.2015.10.075
11. Bobis-Wozowicz S, Kmiotek K, Sekula M, Kedracka-Krok S, Kamycka E, Adamiak M, Jankowska U, Madetko-Talowska A, Sarna M, Bik-Multanowski M, Kolcz J, Boruczkowski D, Madeja Z, Dawn B, Zuba-Surma EK. (2015). Human Induced Pluripotent Stem Cell-Derived Microvesicles Transmit RNAs and Proteins to Recipient Mature Heart Cells Modulating Cell Fate and Behavior. Stem Cells, 33(9):2748-61. https://doi.org/10.1002/stem.2078

Patents and patent applications:

Patent applications:

• “Utilisation of polyelectrolytes as cryoprotectants and method for their use”- współautor (P.431691; patent pending)

Projects:

Principal Investigator:

1. MINIATURA 5, NCN, “Methods of genetic engineering as a tool in studying molecular mechanism of iPS-derived extracellular vesicles impact on umbilical cord blood hematopoietic stem cells”, 2021-2022
2. Young Scientists Grant, MNSiW, “The analysis of the effect and mechanism of action of iPS- derived extracellular vesicles on chemotactic activity of hematopoietic stem cells isolated from umbilical cord blood”, 2016-2017

Investigator:

1. MAESTRO 11 (NCN/2019/34/A/NZ3/00134) (2020-2025) Molecular and cellular mechanisms of pro-regenerative activity of stem cell- derived extracellular vesicles (EVs) in ischemic myocardial injuries: Role of microRNAs
2. STRATEGMED III (STRATEGMED3/303570/7/NCBR/2017) Development of optimized methods for treatment of tissue injuries based on innovative composites and mesenchymal stem cells and their derivatives in patients with civilization diseases (2017-2021)
3. SYMFONIA 3 (NCN/2015/16/W/NZ4/00071) Optimisation of biocompatible scaffolds combinig graphen and defined stem cell populations for tissue regeneration (2015-2020)
4. SONATA-Bis (NCN/UMO-2013/10/E/NZ3/00) Studies of efficacy of microvesicles derived from genetically modified stem cells as carriers for proangiogenic and cardiomyogenic miRNA (2014-2018)
5. TEAM (FNP/TEAM/2012-9/6) Bioactive stem cell- derived microvesicles as novel tool for tissue regeneration (2012-2015)
6. POIG (NCBiR/POIG 01-01-02-00-109/09) Innovative methods for stem cell applications in medicine (2011-2015)
7. OPUS 1 (NCN/2011/01/B/NZ5/04246) Mobilization of  VSELs in children with congenital heart diseases (2011-2014)