Professor Ewa ZUBA-SURMA, PhD

room no. C119A
tel. no. (12) 664 6180

Assistant professor

1999 – Msc
2004 – PhD
degrees awarded by the Jagiellonian University
2009 – habilitation
degree awarded by the Pomeranian Medical University
2020 – Professor degree
degree awarded by the Jagiellonian University

Scientific internships and Awards »

Internships abroad (long-term):

2005 – 2006     post-doctoral internship - Institute of Molecular Cardiology, University of Louisville, KY, USA; Postdoctoral Fellow (1 year)
2006 – 2009    post-doctoral internship - Stem Cell Biology Institute, Brown Cancer Center, University of Louisville, KY, USA; Research Associate (3 years)

The most important prizes and awards:

1999 Scholarship of the Minister of Education for the best students of the Jagiellonian University, Warsaw
2007 Ralph Scott Fellow Research 2nd Award 2007, BCC UofL, Louisville, KY – prize for the best scientific projects in Brown Cancer Center, University of Louisville, KY
2008 ISAC President's Award for Excellence – prize of the President of the ISAC (International Society for Analytical Cytometry) for innovations and achievements with the use of cytometric techniques; ISAC Bethesda, Ml
2008 Scholarship as a part of the Homing Project – granted by the Polish Science Fund for scientists who return from foreign internships; Polish Science Fund, Warsaw;
2009  Habilitation Grant Loreal Poland and the Polish UNESCO Committee for Women and Science (9th editions); Warsaw
2009 Individual Prize of the Vice-Chancellor of the Jagiellonian University for scientific achievements, Krakow
2010 – Individual prize of the President of the Council of Ministers of the Republic of Poland for habilitation thesis; Warsaw
2011 Individual prize of the Vice-chancellor of the Jagiellonian University for scientific achievements, Krakow

Scientific interests »

  • Application of selected populations of stem and progenitor cells in treating acute and chronic heart muscle damages including optimization of identification, isolation and multiplication of stem cells for their application in regenerative treatment of heart and for other purposes related to regenerative medicine.
  • Studies cover identification of subpopulations of stem cells of medullary origin with the increased cariomyogenic and angiogenic potential including mesenchymal stem cells and induced pluripotential stem cells for their possible application in patients.
  • Independent research concern also optimization of isolation methods and the application of Very Small Embryonic-Like Stem Cells; VSELs for regeneration of damaged tissue and organs.
  • For determination of rare cell populations, inter alia, the most advanced methods of flow cytometry, including multi-parameter cell sorting in FACS technology and image analysis with the use of ImageStream system are applied.

Teaching »

Contemporary issues concerning cell biology – application in regenerative medicine (BT365)

Selected publications »

  • Zuba-Surma EK, Wojakowski W, Ratajczak MZ, Dawn B. Very Small Embryonic-Like Stem Cells: Biology and Therapeuthic Potential for Heart Repair. Antioxid Redox Signal. 2011; 15(7):1821-34.
  • Ratajczak MZ, Liu R, Marlicz W, Blogowski W, Starzynska T, Wojakowski W, Zuba-Surma E. Identification of very small embryonic/epiblast-like stem cells (VSELs) circulating in peripheral blood during organ/tissue injuries. Methods Cell Biol. 2011;103:31-54.
  • Ratajczak J, Zuba-Surma E, Klich I, Liu R, Wysoczynski M, Greco N, Kucia M, Laughlin MJ, Ratajczak MZ. Hematopoietic differentiation of umbilical cord blood-derived very small embryonic/epiblast-like stem cells. Leukemia 2011, 25(8):1278-85.
  • Zuba-Surma EK, Guo Y, Taher H, Sanganalmath SK, Hunt G, Vincent RJ, Kucia M, Abdel-Latif A, Tang XL, Ratajczak MZ, Dawn B, Bolli R. Transplantation of expanded bone marrow-derived very small embryonic-like stem cells (VSEL-SCs) improves left ventricular function and remodeling after myocardial infarction. J Cell Mol Med. 2011 15(6):1319-28.
  • Liu Y, Clem B, Zuba-Surma EK, El-Naggar S, Telang S, Jenson AB, Wang Y, Shao H, Ratajczak MZ, Chesney J, Dean DC. Mouse fibroblasts lacking RB1 function form spheres and undergo reprogramming to a cancer stem cell phenotype. Cell Stem Cell. 2009 Apr 3;4(4):336-47.
  • Zuba-Surma EK, Kucia M, Wu W, Klich I, Lillard JW, Ratajczak J, Ratajczak MZ. Very Small Embryonic-Like Stem Cells are present in adult murine organs: ImageStream-based morphological analysis and distribution studies Cytometry A 2008; 73A (12):1116-27.
  • Zuba-Surma EK, Kucia M, Dawn B, Guo Y, Ratajczak MZ, Bolli R. Bone marrow-derived pluripotent very small embryonic-like stem cells (VSELs) are mobilized after acute myocardial infarction. J Mol Cell Cardiol 2008; 44(5): 865-73.
  • Zuba-Surma EK, Kucia M, Abdel-Latif A, Dawn B, Hall B, Singh R, Lillard JW, Ratajczak MZ. Morphological characterization of Very Small Embryonic-Like stem cells (VSELs) by ImageStream system analysis. J Cell Mol Med 2008; 12(1):292-303.
  • Dawn B, Tiwari S, Kucia M, Zuba-Surma EK, Guo Y, SanganalMath SK, Abdel-Latif A, Hunt G, Vincent RJ, Taher H, Reed NJ, Ratajczak MZ, Bolli R. Transplantation of bone marrow-derived very small embryonic-like stem cells (VSELs) attenuates left ventricular dysfunction and remodeling after myocardial infarction. Stem Cells 2008; 26(6):1646-55.
  • Zuba-Surma EK, Abdel-Latif A, Case J, Tiwari S, Hunt G, Vincent RJ, Ranjan S, Srour EF, Bolli R, Dawn B. Sca-1 expression is associated with decreased cardiomyogenic differentiation potential of skeletal muscle-derived adult primitive cells. J Mol Cell Cardiol 2006;41(4):650-60.