Dawid WNUK, MSc

Cell Bank/ATMP laboratory 2.0.8
tel. (12) 664 61 89
e-mail: dawid.wnuk@uj.edu.pl
www: https://orcid.org/0000-0002-5807-2440

2014 – MSc in biology, spec. in cell biology, Faculty of Biology and Earth Sciences, Jagiellonian University
2017 – Management system specialist, Quality System Auditor (International Register of Certificated Auditors - IRCA), manager of systems: Quality Management, Environmental Management and Health and Safety Management (Lloyd's Register Quality Assurance) - Postgraduate studies: "Management and auditing", Institute of Economics, Finance and Management, Faculty of Management and Social Communication, Jagiellonian University


  1. Academic-business internship (October 2015 – March 2016) of Jagiellonian Consortium for Biomolecular and Cellular Research Cell-Mol-Tech (KNOW) of the pro-quality grant of the National Scientific Lead Center in the Field of Biological Sciences. Elpharma
  2. Polish Ministry of Science and Higher Education Scholarship for outstanding achievements (biological sciences) 2017/2018
  3. Doctoral Scholarship ETIUDA7, Polish National Science Center (2019-2020)
  4. PhD Student OPUS9 Scholarship, Polish National Science Centre (2016-2019)
  5. J. Zurzycki Academic Scholarship for Publication Achievements in academic years: 2015/2016 and 2016/2017
  6. Pro-Quality, Jagiellonian University Rector's PhD Scholarship in academic year 2016/2017
  7. Bursary of Federation of European Biochemical Societies 2017; 42nd FEBS Congress 2017
  8. Bursary of Federation of European Biochemical Societies 2019; Lecture Course FEBS/EMBO „Molecular mechanisms of tissue injury, repair and fibrosis” Spetses, Greece


  • Fibroblast to myofibroblast transition (FMT) during wound healing and in the development of fibrotic diseases and bronchial asthma
  • Receptor-dependent signalling pathways and transduction of biochemical signals in normal and cancer cells
  • Use of advanced therapy medical products (ATMP) to treat burns (autologous keratinocytes) and to treat knee degeneration (autologous keratinocytes)
  • Research on plant and lichenic compounds in the treatment of fibrotic diseases and neoplastic diseases (in the partnership with the Faculty of Pharmacy, Jagiellonian University)
  • Phenotypic heterogeneity of the tumor cell populations and their cytostatic resistance (search for effective anti-cancer and anti-tumor active agents)
  • Study of biological properties of newly-synthesized compounds as a potential drug carriers (in the cooperation with the Faculty of Chemistry, Jagiellonian University)
  • In vitro cultures of human bronchial cells (epithelium, fibroblasts) in 3D models: ALI and EMTU as a tool for intercellular interaction studies in respiratory disease models (in the cooperation with the Department of Pulmonology of the Jagiellonian University Hospital, Collegium Medicum)


  1. Piska Kamil, Koczurkiewicz Paulina, Wnuk Dawid, Karnas Elżbieta, Bucki Adam, Wójcik-Pszczoła Katarzyna, Jamrozik Marek, Michalik Marta, Kołaczkowski Marcin, Pękala Elżbieta (2019) Synergistic anticancer activity of doxorubicin and piperlongumine on DU-145 prostate cancer cells - The involvement of carbonyl reductase 1 inhibition, Chemico Biological Interactions; https://doi.org/10.1016/j.cbi.2019.01.003
  2. Wiktor Anna, Sarna Michał, Wnuk Dawid, Sarna Tadeusz (2018) Lipofuscin-mediated photodynamic stress induces adverse changes in nanomechanical properties of retinal pigment epithelium cells, Scientific Reports, https://doi.org/10.1038/s41598-018-36322-2
  3. Kwolek Urszula; Nakai Keita; Pluta Anna; Zatorska Maria; Wnuk Dawid; Lasota Sławomir, Bednar Jan, Michalik Marta, Yusa Shin-ichi; Kepczynski Mariusz (2017) Polyion Complex Vesicles (PICsomes) from Strong Copolyelectrolytes, Colloids and Surfaces B: Biointerfaces, https://doi.org/10.1016/j.colsurfb.2017.07.042
  4. Paw Milena; Borek Izabela; Wnuk Dawid; Ryszawy Damian; Piwowarczyk Katarzyna; Kmiotek Katarzyna; Wojcik-Pszczola Katarzyna; Pierzchalska Malgorzata; Madeja Zbigniew; Sanak Marek; Blyszczuk Przemyslaw; Michalik Marta; Czyz Jaroslaw (2017) Connexin43 Controls the Myofibroblastic Differentiation of Bronchial Fibroblasts from Asthmatic Patients, American Journal of Respiratory Cell and Molecular Biology https://doi.org/10.1165/rcmb.2015-0255OC
  5. Galanty Agnieszka; Koczurkiewicz Paulina; Wnuk Dawid; Paw Milena; Karnas Elzbieta; Podolak Irma; Wegrzyn Michal; Borusiewicz Magdalena; Madeja Zbigniew; Czyz Jaroslaw; Michalik Marta; (2017) Usnic acid and atranorin exert selective cytostatic and anti-invasive effects on human prostate and melanoma cancer cells, Toxicology in Vitro, https://doi.org/10.1016/j.tiv.2017.01.008
  6. Sarna Michal; Olchawa Magdalena; Zadlo Andrzej; Wnuk Dawid; Sarna Tadeusz; (2017) The nanomechanical role of melanin granules in the retinal pigment epithelium, Nanomedicine: Nanotechnology, Biology and Medicine, https://doi.org/10.1016/j.nano.2016.11.020
  7. Koczurkiewicz Paulina; Kowolik Ewa; Podolak Irma; Wnuk Dawid; Piska Kamil; Labedz-Maslowska Anna; Wojcik-Pszczola Katarzyna; Pekala Elzbieta; Czyz Jaroslaw; Michalik Marta; (2016) Synergistic cytotoxic and anti-invasive effects of mitoxantrone and triterpene saponins from Lysimachia ciliata on human prostate cancer cells, Planta Medica, DOI: 10.1055/s-0042-117537
  8. Pilat Anna; Sarna Michal; Wnuk Dawid; Sarna Tadeusz; (2016) 178-Oxidative, Morphological and Mechanical Changes in ARPE-19 Cells Induced by Lipofuscin-Mediated Photic Stress, Free Radical Biology and Medicine, https://doi.org/10.1016/j.freeradbiomed.2016.10.219
  9. Wnuk Dawid; Kmiotek Katarzyna; Ryszawy Damian; Paw Milena; Michalik Marta; (2016) Inhibition of RhoA pathway decreases formin-related genes expression and TGF-β1-induced fibroblast to myofibroblast transition of bronchial fibroblasts derived from asthmatic patients, Respirology, 21, 213-213 (conference)
  10. Ryszawy Damian; Wnuk Dawid; Karnas Elzbieta; Paw Milena; Madeja Zbigniew; Michalik Marta; (2016) Endocytosis may be involved in asthma development by regulation of TGF-β-dependent human bronchial fibroblasts to miofibroblast transition, Respirology, 21, 213-213 (conference)
  11. Pilat Anna; Sarna Michal; Wnuk Dawid; Olchawa Magdalena; Sarna Tadeusz; (2016) Aging and antioxidants differentially modulate the effect of phagocytized lipofuscin granules on expression of antioxidant enzymes in ARPE-19 cells, Investigative Ophthalmology & Visual Science, 57, 12, 6044-6044 (conference)
  12. Wojcik-Pszczola Katarzyna; Hincza Kinga; Wnuk Dawid; Kadziolka Dominika; Koczurkiewicz Paulina; Sanak Marek; Madeja Zbigniew; Pekala Elzbieta; Michalik Marta; (2016) Pentoxifylline and its active metabolite lisofylline attenuate transforming growth factor β1-induced asthmatic bronchial fibroblast-to-myofibroblast transition, Acta Biochimica Polonica, https://doi.org/10.18388/abp.2016_1357
  13. Sarna Michal; Wojcik Katarzyna; Hermanowicz Pawel; Wnuk Dawid; Burda Kvetoslava; Sanak Marek; Czyz Jaroslaw; Michalik Marta; (2015) Undifferentiated bronchial fibroblasts derived from asthmatic patients display higher elastic modulus than their non-asthmatic counterparts, PLoS One, https://doi.org/10.1371/journal.pone.0116840